Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1

24(S)-hydroxycholesterol (24S-OHC), which is enzymatically produced in the brain, has an important role in maintaining brain cholesterol homeostasis. We have previously reported that 24S-OHC induces necroptosis in human neuroblastoma SH-SY5Y cells. In the present study, we investigated the mechanism...

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Detalles Bibliográficos
Autores principales: Yamanaka, K, Urano, Y, Takabe, W, Saito, Y, Noguchi, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040651/
https://www.ncbi.nlm.nih.gov/pubmed/24407243
http://dx.doi.org/10.1038/cddis.2013.524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040651/
https://www.ncbi.nlm.nih.gov/pubmed/24407243
http://dx.doi.org/10.1038/cddis.2013.524

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