Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain

The glutamate-induced excitotoxicity pathway has been reported in several neurodegenerative diseases. Molecules that inhibit the release of glutamate or cause the overactivation of glutamate receptors can minimize neuronal cell death in these diseases. Osmotin, a homolog of mammalian adiponectin, is...

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Detalles Bibliográficos
Autores principales: Shah, S A, Lee, H Y, Bressan, R A, Yun, D J, Kim, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040667/
https://www.ncbi.nlm.nih.gov/pubmed/24481440
http://dx.doi.org/10.1038/cddis.2013.538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040667/
https://www.ncbi.nlm.nih.gov/pubmed/24481440
http://dx.doi.org/10.1038/cddis.2013.538

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