Interleukin-1β promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production

Glioblastoma is the most common brain tumor in adults. Advanced glioblastomas normally contain hypoxic areas. The primary cellular responses to hypoxia are generally mediated by the transcription factor hypoxia-inducible factor 1 (HIF-1). Interleukin-1β (IL-1β) is a cytokine that is often present in...

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Detalles Bibliográficos
Autores principales: Sun, W, Depping, R, Jelkmann, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040669/
https://www.ncbi.nlm.nih.gov/pubmed/24457964
http://dx.doi.org/10.1038/cddis.2013.562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040669/
https://www.ncbi.nlm.nih.gov/pubmed/24457964
http://dx.doi.org/10.1038/cddis.2013.562

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