Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyc...

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Detalles Bibliográficos
Autores principales: Doti, N, Reuther, C, Scognamiglio, P L, Dolga, A M, Plesnila, N, Ruvo, M, Culmsee, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040673/
https://www.ncbi.nlm.nih.gov/pubmed/24434516
http://dx.doi.org/10.1038/cddis.2013.518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040673/
https://www.ncbi.nlm.nih.gov/pubmed/24434516
http://dx.doi.org/10.1038/cddis.2013.518

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