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JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

Our aim was to better understand the mechanism and importance of sustained c-Jun N-terminal kinase (JNK) activation in endoplasmic reticulum (ER) stress and effects of ER stress on mitochondria by determining the role of mitochondrial JNK binding protein, Sab. Tunicamycin or brefeldin A induced a ra...

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Detalles Bibliográficos
Autores principales: Win, S, Than, T A, Fernandez-Checa, J C, Kaplowitz, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040675/
https://www.ncbi.nlm.nih.gov/pubmed/24407242
http://dx.doi.org/10.1038/cddis.2013.522