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Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal kinase and poly (ADP-ribose) polymerase-1-mediated pathway

Advanced oxidation protein products (AOPPs), a novel protein marker of oxidative damage, have been confirmed to accumulate in patients with inflammatory bowel disease (IBD), as well as those with diabetes and chronic kidney disease. However, the role of AOPPs in the intestinal epithelium remains unc...

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Detalles Bibliográficos
Autores principales: Xie, F, Sun, S, Xu, A, Zheng, S, Xue, M, Wu, P, Zeng, J H, Bai, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040683/
https://www.ncbi.nlm.nih.gov/pubmed/24434514
http://dx.doi.org/10.1038/cddis.2013.542