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miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase

hTERT is the catalytic subunit of the telomerase complex. Elevated expression of hTERT is associated with the expansion and metastasis of gastric tumor. In this study, we aimed to identify novel tumor suppressor miRNAs that restrain hTERT expression. We began our screen for hTERT-targeting miRNAs wi...

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Detalles Bibliográficos
Autores principales: Chen, L, Lü, M-H, Zhang, D, Hao, N-B, Fan, Y-H, Wu, Y-Y, Wang, S-M, Xie, R, Fang, D-C, Zhang, H, Hu, C-J, Yang, S-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040688/
https://www.ncbi.nlm.nih.gov/pubmed/24481448
http://dx.doi.org/10.1038/cddis.2013.553