Cargando…

c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo

Altered synaptic function is considered one of the first features of Alzheimer disease (AD). Currently, no treatment is available to prevent the dysfunction of excitatory synapses in AD. Identification of the key modulators of synaptopathy is of particular significance in the treatment of AD. We her...

Descripción completa

Detalles Bibliográficos
Autores principales: Sclip, A, Tozzi, A, Abaza, A, Cardinetti, D, Colombo, I, Calabresi, P, Salmona, M, Welker, E, Borsello, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040696/
https://www.ncbi.nlm.nih.gov/pubmed/24457963
http://dx.doi.org/10.1038/cddis.2013.559