The fine-tuning of TRAF2–GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex

We provide the first biochemical evidence of a direct interaction between the glutathione transferase P1-1 (GSTP1-1) and the TRAF domain of TNF receptor-associated factor 2 (TRAF2), and describe how ligand binding modulates such an equilibrium. The dissociation constant of the heterocomplex is K(d)=...

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Detalles Bibliográficos
Autores principales: De Luca, A, Mei, G, Rosato, N, Nicolai, E, Federici, L, Palumbo, C, Pastore, A, Serra, M, Caccuri, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040697/
https://www.ncbi.nlm.nih.gov/pubmed/24457959
http://dx.doi.org/10.1038/cddis.2013.529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040697/
https://www.ncbi.nlm.nih.gov/pubmed/24457959
http://dx.doi.org/10.1038/cddis.2013.529

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