Nox4 and redox signaling mediate TGF-β-induced endothelial cell apoptosis and phenotypic switch

Transforming growth factor-β (TGF-β) triggers apoptosis in endothelial cells, while the mechanisms underlying this action are not entirely understood. Using genetic and pharmacological tools, we demonstrated that TGF-β induced a moderate apoptotic response in human cultured endothelial cells, which...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, F, Wang, Y, Wu, X, Peshavariya, H M, Dusting, G J, Zhang, M, Jiang, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040700/
https://www.ncbi.nlm.nih.gov/pubmed/24457954
http://dx.doi.org/10.1038/cddis.2013.551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040700/
https://www.ncbi.nlm.nih.gov/pubmed/24457954
http://dx.doi.org/10.1038/cddis.2013.551

Ejemplares similares