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Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
The Wnt1 protein, a secreted ligand that activates Wnt signaling pathways, contributes to the self-renewal of cancer stem cells (CSCs) and thus may be a major determinant of tumor progression and chemoresistance. In a series of gastric cancer specimens, we found strong correlations among Wnt1 expres...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040703/ https://www.ncbi.nlm.nih.gov/pubmed/24481453 http://dx.doi.org/10.1038/cddis.2013.515 |