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Systemic gene delivery to the central nervous system using Adeno-associated virus

Adeno-associated virus (AAV)-mediated gene delivery has emerged as an effective and safe tool for both preclinical and clinical studies of neurological disorders. The recent discovery that several serotypes are able to cross the blood–brain barrier when administered systemically has been a real brea...

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Detalles Bibliográficos
Autores principales: Bourdenx, Mathieu, Dutheil, Nathalie, Bezard, Erwan, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040820/
https://www.ncbi.nlm.nih.gov/pubmed/24917785
http://dx.doi.org/10.3389/fnmol.2014.00050