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Microglia change from a reactive to an age-like phenotype with the time in culture

Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senesc...

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Detalles Bibliográficos
Autores principales: Caldeira, Cláudia, Oliveira, Ana F., Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Fernandes, Adelaide, Brites, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040822/
https://www.ncbi.nlm.nih.gov/pubmed/24917789
http://dx.doi.org/10.3389/fncel.2014.00152