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Microglia change from a reactive to an age-like phenotype with the time in culture
Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senesc...
Autores principales: | Caldeira, Cláudia, Oliveira, Ana F., Cunha, Carolina, Vaz, Ana R., Falcão, Ana S., Fernandes, Adelaide, Brites, Dora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040822/ https://www.ncbi.nlm.nih.gov/pubmed/24917789 http://dx.doi.org/10.3389/fncel.2014.00152 |
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