Population-Genetic Inference from Pooled-Sequencing Data

Although pooled-population sequencing has become a widely used approach for estimating allele frequencies, most work has proceeded in the absence of a proper statistical framework. We introduce a self-sufficient, closed-form, maximum-likelihood estimator for allele frequencies that accounts for erro...

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Detalles Bibliográficos
Autores principales: Lynch, Michael, Bost, Darius, Wilson, Sade, Maruki, Takahiro, Harrison, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040993/
https://www.ncbi.nlm.nih.gov/pubmed/24787620
http://dx.doi.org/10.1093/gbe/evu085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040993/
https://www.ncbi.nlm.nih.gov/pubmed/24787620
http://dx.doi.org/10.1093/gbe/evu085

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