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Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice

BACKGROUND: The ubiquitin-proteasome pathway (UPP) is a major protein degradation pathway that is activated during sepsis and has been proposed as a therapeutic target for preventing skeletal muscle loss due to cachexia. Although several studies have investigated the modulation of proteasome activit...

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Detalles Bibliográficos
Autores principales: Jamart, Cécile, Gomes, Aldrin V, Dewey, Shannamar, Deldicque, Louise, Raymackers, Jean-Marc, Francaux, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041039/
https://www.ncbi.nlm.nih.gov/pubmed/24885455
http://dx.doi.org/10.1186/1471-2474-15-166