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Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice
BACKGROUND: The ubiquitin-proteasome pathway (UPP) is a major protein degradation pathway that is activated during sepsis and has been proposed as a therapeutic target for preventing skeletal muscle loss due to cachexia. Although several studies have investigated the modulation of proteasome activit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041039/ https://www.ncbi.nlm.nih.gov/pubmed/24885455 http://dx.doi.org/10.1186/1471-2474-15-166 |