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DNA methylation of the allergy regulatory gene interferon gamma varies by age, sex, and tissue type in asthmatics

BACKGROUND: Asthma is associated with allergic sensitization in about half of all cases, and asthma phenotypes can vary by age and sex. DNA methylation in the promoter of the allergy regulatory gene interferon gamma (IFNγ) has been linked to the maintenance of allergic immune function in human cell...

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Detalles Bibliográficos
Autores principales: Lovinsky-Desir, Stephanie, Ridder, Robert, Torrone, David, Maher, Christina, Narula, Surinder, Scheuerman, Melissa, Merle, David, Kattan, Meyer, DiMango, Emily, Miller, Rachel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041041/
https://www.ncbi.nlm.nih.gov/pubmed/24891923
http://dx.doi.org/10.1186/1868-7083-6-9