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Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis

BACKGROUND: Birch pollen allergies are frequently associated with adverse reactions to various fruits, nuts, or vegetables, described as pollen–food syndrome (PFS) and caused by cross-reactive IgE antibodies primarily directed against Bet v 1. Specific immunotherapy (SIT) represents an effective tre...

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Detalles Bibliográficos
Autores principales: Roulias, A, Pichler, U, Hauser, M, Himly, M, Hofer, H, Lackner, P, Ebner, C, Briza, P, Bohle, B, Egger, M, Wallner, M, Ferreira, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041322/
https://www.ncbi.nlm.nih.gov/pubmed/24224690
http://dx.doi.org/10.1111/all.12306