Crystal structure of a 4-thiouridine synthetase–RNA complex reveals specificity of tRNA U8 modification

In prokaryotes and archaea transfer ribonucleic acid (tRNA) stability as well as cellular UV protection relies on the post-transcriptional modification of uracil at position 8 (U8) of tRNAs by the 4-thiouridine synthetase ThiI. Here, we report three crystal structures of ThiI from Thermotoga maritim...

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Detalles Bibliográficos
Autores principales: Neumann, Piotr, Lakomek, Kristina, Naumann, Peter-Thomas, Erwin, Whitney M., Lauhon, Charles T., Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041423/
https://www.ncbi.nlm.nih.gov/pubmed/24705700
http://dx.doi.org/10.1093/nar/gku249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041423/
https://www.ncbi.nlm.nih.gov/pubmed/24705700
http://dx.doi.org/10.1093/nar/gku249

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