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Crystal structure of a 4-thiouridine synthetase–RNA complex reveals specificity of tRNA U8 modification
In prokaryotes and archaea transfer ribonucleic acid (tRNA) stability as well as cellular UV protection relies on the post-transcriptional modification of uracil at position 8 (U8) of tRNAs by the 4-thiouridine synthetase ThiI. Here, we report three crystal structures of ThiI from Thermotoga maritim...
Autores principales: | Neumann, Piotr, Lakomek, Kristina, Naumann, Peter-Thomas, Erwin, Whitney M., Lauhon, Charles T., Ficner, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041423/ https://www.ncbi.nlm.nih.gov/pubmed/24705700 http://dx.doi.org/10.1093/nar/gku249 |
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