Synthesis of an oligonucleotide-derivatized amphipol and its use to trap and immobilize membrane proteins

Amphipols (APols) are specially designed amphipathic polymers that stabilize membrane proteins (MPs) in aqueous solutions in the absence of detergent. A8–35, a polyacrylate-based APol, has been grafted with an oligodeoxynucleotide (ODN). The synthesis, purification and properties of the resulting ‘O...

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Detalles Bibliográficos
Autores principales: Bon, Christel Le, Della Pia, Eduardo Antonio, Giusti, Fabrice, Lloret, Noémie, Zoonens, Manuela, Martinez, Karen L., Popot, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041424/
https://www.ncbi.nlm.nih.gov/pubmed/24744236
http://dx.doi.org/10.1093/nar/gku250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041424/
https://www.ncbi.nlm.nih.gov/pubmed/24744236
http://dx.doi.org/10.1093/nar/gku250

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