Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export

The conserved Sac3:Thp1:Sem1:Sus1:Cdc31 (TREX2) complex binds to nuclear pore complexes (NPCs) and, in addition to integrating mRNA nuclear export with preceding steps in the gene expression pathway, facilitates re-positioning of highly regulated actively transcribing genes (such as GAL1) to NPCs. A...

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Detalles Bibliográficos
Autores principales: Jani, Divyang, Valkov, Eugene, Stewart, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041426/
https://www.ncbi.nlm.nih.gov/pubmed/24705649
http://dx.doi.org/10.1093/nar/gku252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041426/
https://www.ncbi.nlm.nih.gov/pubmed/24705649
http://dx.doi.org/10.1093/nar/gku252

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