KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis

Various types of human cancers exhibit amplification or deletion of KDM4A-D members, which selectively demethylate H3K9 and H3K36, thus implicating their activity in promoting carcinogenesis. On this basis, it was hypothesized that dysregulated expression of KDM4A-D family promotes chromosomal insta...

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Detalles Bibliográficos
Autores principales: Kupershmit, Ilana, Khoury-Haddad, Hanan, Awwad, Samah W., Guttmann-Raviv, Noga, Ayoub, Nabieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041427/
https://www.ncbi.nlm.nih.gov/pubmed/24728997
http://dx.doi.org/10.1093/nar/gku253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041427/
https://www.ncbi.nlm.nih.gov/pubmed/24728997
http://dx.doi.org/10.1093/nar/gku253

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