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A family of synthetic riboswitches adopts a kinetic trapping mechanism
Riboswitches are sequences of RNA that control gene expression via RNA–ligand interactions, without the need for accessory proteins. Riboswitches consist of an aptamer that recognizes the ligand and an expression platform that couples ligand binding to a change in gene expression. Using in vitro sel...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041436/ https://www.ncbi.nlm.nih.gov/pubmed/24782524 http://dx.doi.org/10.1093/nar/gku262 |