5-Fluorouracil affects assembly of stress granules based on RNA incorporation

The antimetabolite 5-fluorouracil is a widely used chemotherapeutic for the treatment of several solid cancers. However, resistance to 5-fluorouracil remains a major drawback in its clinical use. In this study we report that treatment of HeLa cells with 5-fluorouracil resulted in de novo assembly of...

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Detalles Bibliográficos
Autores principales: Kaehler, Christian, Isensee, Jörg, Hucho, Tim, Lehrach, Hans, Krobitsch, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041438/
https://www.ncbi.nlm.nih.gov/pubmed/24728989
http://dx.doi.org/10.1093/nar/gku264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041438/
https://www.ncbi.nlm.nih.gov/pubmed/24728989
http://dx.doi.org/10.1093/nar/gku264

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