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Induction of Neutralizing Antibody Response against Four Dengue Viruses in Mice by Intramuscular Electroporation of Tetravalent DNA Vaccines

DNA vaccine against dengue is an interesting strategy for a prime/boost approach. This study evaluated neutralizing antibody (NAb) induction of a dengue tetravalent DNA (TDNA) vaccine candidate administered by intramuscular-electroporation (IM-EP) and the benefit of homologous TDNA boosting in mice....

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Detalles Bibliográficos
Autores principales: Prompetchara, Eakachai, Ketloy, Chutitorn, Keelapang, Poonsook, Sittisombut, Nopporn, Ruxrungtham, Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041562/
https://www.ncbi.nlm.nih.gov/pubmed/24887426
http://dx.doi.org/10.1371/journal.pone.0092643