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Mathematical modeling of the effects of glutathione on arsenic methylation

BACKGROUND: Arsenic is a major environmental toxin that is detoxified in the liver by biochemical mechanisms that are still under study. In the traditional metabolic pathway, arsenic undergoes two methylation reactions, each followed by a reduction, after which it is exported and released in the uri...

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Detalles Bibliográficos
Autores principales: Lawley, Sean D, Yun, Jina, Gamble, Mary V, Hall, Megan N, Reed, Michael C, Nijhout, H Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041632/
https://www.ncbi.nlm.nih.gov/pubmed/24885596
http://dx.doi.org/10.1186/1742-4682-11-20