Direct Sequencing from the Minimal Number of DNA Molecules Needed to Fill a 454 Picotiterplate

The large amount of DNA needed to prepare a library in next generation sequencing protocols hinders direct sequencing of small DNA samples. This limitation is usually overcome by the enrichment of such samples with whole genome amplification (WGA), mostly by multiple displacement amplification (MDA)...

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Detalles Bibliográficos
Autores principales: Džunková, Mária, Garcia-Garcerà, Marc, Martínez-Priego, Llúcia, D’Auria, Giussepe, Calafell, Francesc, Moya, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041646/
https://www.ncbi.nlm.nih.gov/pubmed/24887077
http://dx.doi.org/10.1371/journal.pone.0097379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041646/
https://www.ncbi.nlm.nih.gov/pubmed/24887077
http://dx.doi.org/10.1371/journal.pone.0097379

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