Human Cytomegalovirus Replication Is Strictly Inhibited by siRNAs Targeting UL54, UL97 or UL122/123 Gene Transcripts

Human cytomegalovirus (HCMV) causes severe sequelae in immunocompromised hosts. Current antiviral therapies have serious adverse effects, with treatment in many clinical settings problematic, making new therapeutic approaches necessary. We examined the in vitro efficacy of small interfering RNAs (si...

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Detalles Bibliográficos
Autores principales: Hamilton, Stuart T., Milbradt, Jens, Marschall, Manfred, Rawlinson, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041654/
https://www.ncbi.nlm.nih.gov/pubmed/24887060
http://dx.doi.org/10.1371/journal.pone.0097231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041654/
https://www.ncbi.nlm.nih.gov/pubmed/24887060
http://dx.doi.org/10.1371/journal.pone.0097231

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