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Preclinical Therapeutic Potential of a Nitrosylating Agent in the Treatment of Ovarian Cancer

This study examines the role of s-nitrosylation in the growth of ovarian cancer using cell culture based and in vivo approaches. Using the nitrosylating agent, S-nitrosoglutathione (GSNO), a physiological nitric oxide molecule, we show that GSNO treatment inhibited proliferation of chemoresponsive a...

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Detalles Bibliográficos
Autores principales: Giri, Shailendra, Rattan, Ramandeep, Deshpande, Mandar, Maguire, Jacie L., Johnson, Zachary, Graham, Rondell P., Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041717/
https://www.ncbi.nlm.nih.gov/pubmed/24887420
http://dx.doi.org/10.1371/journal.pone.0097897