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Stilbene Induced Inhibition of Androgen Receptor Dimerization: Implications for AR and ARΔLBD-Signalling in Human Prostate Cancer Cells

BACKGROUND: Advanced castration resistant prostate cancer (CRPC) is often characterized by an increase of C-terminally truncated, constitutively active androgen receptor (AR) variants. Due to the absence of a ligand binding domain located in the AR-C-terminus, these receptor variants (also termed AR...

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Detalles Bibliográficos
Autores principales: Streicher, Wolfgang, Luedeke, Manuel, Azoitei, Anca, Zengerling, Friedemann, Herweg, Alexander, Genze, Felicitas, Schrader, Mark G., Schrader, Andres J., Cronauer, Marcus V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041728/
https://www.ncbi.nlm.nih.gov/pubmed/24887556
http://dx.doi.org/10.1371/journal.pone.0098566