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Loss of Sonic Hedgehog Leads to Alterations in Intestinal Secretory Cell Maturation and Autophagy

BACKGROUND: Intestinal epithelial cells express the Sonic and Indian hedgehog ligands. Despite the strong interest in gut hedgehog signaling in GI diseases, no studies have specifically addressed the singular role of intestinal epithelial cell Sonic hedgehog signaling. The aim of this study was to i...

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Detalles Bibliográficos
Autores principales: Gagné-Sansfaçon, Jessica, Allaire, Joannie M., Jones, Christine, Boudreau, François, Perreault, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041759/
https://www.ncbi.nlm.nih.gov/pubmed/24887421
http://dx.doi.org/10.1371/journal.pone.0098751