Cargando…

Ligand-Independent Canonical Wnt Activity in Canine Mammary Tumor Cell Lines Associated with Aberrant LEF1 Expression

Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechanisms during canine mammary tumorigenesis, in this study we assessed the incidence and the mechanism o...

Descripción completa

Detalles Bibliográficos
Autores principales: Gracanin, Ana, Timmermans-Sprang, Elpetra P. M., van Wolferen, Monique E., Rao, Nagesha A. S., Grizelj, Juraj, Vince, Silvijo, Hellmen, Eva, Mol, Jan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041801/
https://www.ncbi.nlm.nih.gov/pubmed/24887235
http://dx.doi.org/10.1371/journal.pone.0098698