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Functional annotation signatures of disease susceptibility loci improve SNP association analysis

BACKGROUND: Genetic association studies are conducted to discover genetic loci that contribute to an inherited trait, identify the variants behind these associations and ascertain their functional role in determining the phenotype. To date, functional annotations of the genetic variants have rarely...

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Detalles Bibliográficos
Autores principales: Iversen, Edwin S, Lipton, Gary, Clyde, Merlise A, Monteiro, Alvaro NA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041996/
https://www.ncbi.nlm.nih.gov/pubmed/24886216
http://dx.doi.org/10.1186/1471-2164-15-398