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Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research
BACKGROUND: The DA rat strain is particularly susceptible to the induction of a number of chronic inflammatory diseases, such as models for rheumatoid arthritis and multiple sclerosis. Here we sequenced the genomes of two DA sub-strains and two disease resistant strains, E3 and PVG, previously used...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041999/ https://www.ncbi.nlm.nih.gov/pubmed/24885425 http://dx.doi.org/10.1186/1471-2164-15-391 |