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Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research

BACKGROUND: The DA rat strain is particularly susceptible to the induction of a number of chronic inflammatory diseases, such as models for rheumatoid arthritis and multiple sclerosis. Here we sequenced the genomes of two DA sub-strains and two disease resistant strains, E3 and PVG, previously used...

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Detalles Bibliográficos
Autores principales: Bäckdahl, Liselotte, Ekman, Diana, Jagodic, Maja, Olsson, Tomas, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041999/
https://www.ncbi.nlm.nih.gov/pubmed/24885425
http://dx.doi.org/10.1186/1471-2164-15-391