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Improved methodology to obtain large quantities of correctly folded recombinant N-terminal extracellular domain of the human muscle acetylcholine receptor for inducing experimental autoimmune myasthenia gravis in rats
INTRODUCTION: Human myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular system. Experimental autoimmune myasthenia gravis (EAMG) is a well-established animal model for MG that can be induced by active immunization with the Torpedo californica-derived acetylcholine receptor (AChR)....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042039/ https://www.ncbi.nlm.nih.gov/pubmed/24904677 http://dx.doi.org/10.5114/aoms.2013.36921 |