Improved methodology to obtain large quantities of correctly folded recombinant N-terminal extracellular domain of the human muscle acetylcholine receptor for inducing experimental autoimmune myasthenia gravis in rats

INTRODUCTION: Human myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular system. Experimental autoimmune myasthenia gravis (EAMG) is a well-established animal model for MG that can be induced by active immunization with the Torpedo californica-derived acetylcholine receptor (AChR)....

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Detalles Bibliográficos
Autores principales: Sun, Chenjing, Zhang, Hongliang, Xu, Jiang, Gao, Jie, Qi, Xiaokun, Li, Zhuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Experimental Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042039/
https://www.ncbi.nlm.nih.gov/pubmed/24904677
http://dx.doi.org/10.5114/aoms.2013.36921

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