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Tumor suppression in skin and other tissues via cross-talk between vitamin D- and p53-signaling

P53 and its family members have been implicated in the direct regulation of the vitamin D receptor (VDR). Vitamin D- and p53-signaling pathways have a significant impact on spontaneous or carcinogen-induced malignant transformation of cells, with VDR and p53 representing important tumor suppressors....

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Detalles Bibliográficos
Autores principales: Reichrath, Jörg, Reichrath, Sandra, Heyne, Kristina, Vogt, Thomas, Roemer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042062/
https://www.ncbi.nlm.nih.gov/pubmed/24917821
http://dx.doi.org/10.3389/fphys.2014.00166