Generation of neural progenitor cells by chemical cocktails and hypoxia

Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts by a chemical cocktail, namely VCR (V, VPA, an inhibitor of HDACs; C, CHIR99021, an inhibitor of GSK-3 kinases and R, Repsox, an inhibitor o...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042166/
https://www.ncbi.nlm.nih.gov/pubmed/24638034
http://dx.doi.org/10.1038/cr.2014.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042166/
https://www.ncbi.nlm.nih.gov/pubmed/24638034
http://dx.doi.org/10.1038/cr.2014.32

Ejemplares similares