TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells

Multiple myeloma (MM) is a clonal plasma cell malignancy that is initiated by a number of mutations and the process of disease progression is characterized by further acquisition of mutations. The identification and functional characterization of these myelomagenic mutations is necessary to better u...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, X, Blackburn, P R, Tschumper, R C, Ekker, S C, Jelinek, D F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042302/
https://www.ncbi.nlm.nih.gov/pubmed/24813078
http://dx.doi.org/10.1038/bcj.2014.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042302/
https://www.ncbi.nlm.nih.gov/pubmed/24813078
http://dx.doi.org/10.1038/bcj.2014.32

Ejemplares similares