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TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells
Multiple myeloma (MM) is a clonal plasma cell malignancy that is initiated by a number of mutations and the process of disease progression is characterized by further acquisition of mutations. The identification and functional characterization of these myelomagenic mutations is necessary to better u...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042302/ https://www.ncbi.nlm.nih.gov/pubmed/24813078 http://dx.doi.org/10.1038/bcj.2014.32 |