Cargando…

Regulatory interplay between TFIID’s conformational transitions and its modular interaction with core promoter DNA

Recent structural and biochemical studies of human TFIID have significantly increased our understanding of the mechanisms underlying the recruitment of TFIID to promoter DNA and its role in transcription initiation. Structural studies using cryo-EM revealed that modular interactions underlie TFIID’s...

Descripción completa

Detalles Bibliográficos
Autores principales: Cianfrocco, Michael A, Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042585/
https://www.ncbi.nlm.nih.gov/pubmed/23863784
http://dx.doi.org/10.4161/trns.25291