Counter-regulation of T cell effector function by differentially activated p38

Unlike the MAP kinase (MAPK) cascade that phosphorylates p38 on the activation loop, T cell receptor (TCR) signaling results in phosphorylation on Tyr-323 (pY323, alternative pathway). Using mice expressing p38α and p38β with Y323F substitutions, we show that alternatively but not MAPK cascade-activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Alam, Muhammad S., Gaida, Matthias M., Ogawa, Youichi, Kolios, Antonios G.A., Lasitschka, Felix, Ashwell, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042639/
https://www.ncbi.nlm.nih.gov/pubmed/24863062
http://dx.doi.org/10.1084/jem.20131917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042639/
https://www.ncbi.nlm.nih.gov/pubmed/24863062
http://dx.doi.org/10.1084/jem.20131917

Ejemplares similares