Identification of 2R-ohnologue gene families displaying the same mutation-load skew in multiple cancers

The complexity of signalling pathways was boosted at the origin of the vertebrates, when two rounds of whole genome duplication (2R-WGD) occurred. Those genes and proteins that have survived from the 2R-WGD—termed 2R-ohnologues—belong to families of two to four members, and are enriched in signallin...

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Detalles Bibliográficos
Autores principales: Tinti, Michele, Dissanayake, Kumara, Synowsky, Silvia, Albergante, Luca, MacKintosh, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042849/
https://www.ncbi.nlm.nih.gov/pubmed/24806839
http://dx.doi.org/10.1098/rsob.140029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042849/
https://www.ncbi.nlm.nih.gov/pubmed/24806839
http://dx.doi.org/10.1098/rsob.140029

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