Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line

Striated muscle tissues undergo adaptive remodelling in response to mechanical load. This process involves the myofilament titin and, specifically, its kinase domain (TK; titin kinase) that translates mechanical signals into regulatory pathways of gene expression in the myofibril. TK mechanosensing...

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Detalles Bibliográficos
Autores principales: Bogomolovas, Julijus, Gasch, Alexander, Simkovic, Felix, Rigden, Daniel J., Labeit, Siegfried, Mayans, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042850/
https://www.ncbi.nlm.nih.gov/pubmed/24850911
http://dx.doi.org/10.1098/rsob.140041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042850/
https://www.ncbi.nlm.nih.gov/pubmed/24850911
http://dx.doi.org/10.1098/rsob.140041

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