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RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

The RNA polymerase II largest subunit (Rpb1) contains a unique C-terminal domain (CTD) that plays multiple roles during transcription. The CTD is composed of consensus Y(1)S(2)P(3)T(4)S(5)P(6)S(7) repeats, in which Ser, Thr and Tyr residues can all be phosphorylated. Here we report analysis of CTD T...

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Detalles Bibliográficos
Autores principales: Hsin, Jing-Ping, Li, Wencheng, Hoque, Mainul, Tian, Bin, Manley, James L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042873/
https://www.ncbi.nlm.nih.gov/pubmed/24842995
http://dx.doi.org/10.7554/eLife.02112