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Prostasin may contribute to chemoresistance, repress cancer cells in ovarian cancer, and is involved in the signaling pathways of CASP/PAK2-p34/actin

Ovarian cancer is the deadliest of gynecologic cancers, largely due to the development of drug resistance in chemotherapy. Prostasin may have an essential role in the oncogenesis. In this study, we show that prostasin is decreased in an ovarian cancer drug-resistant cell line and in ovarian cancer p...

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Detalles Bibliográficos
Autores principales: Yan, B-x, Ma, J-x, Zhang, J, Guo, Y, Mueller, M D, Remick, S C, Yu, J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043260/
https://www.ncbi.nlm.nih.gov/pubmed/24434518
http://dx.doi.org/10.1038/cddis.2013.523