A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

BACKGROUND: We recently reported that epithelial–mesenchymal transition (EMT) is active in the airways in chronic obstructive pulmonary disease (COPD), suggesting presence of an active profibrotic and promalignant stroma. With no data available on potential treatment effects, we undertook a blinded...

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Detalles Bibliográficos
Autores principales: Sohal, Sukhwinder Singh, Soltani, Amir, Reid, David, Ward, Chris, Wills, Karen E, Muller, H Konrad, Walters, Eugene Haydn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://www.ncbi.nlm.nih.gov/pubmed/24920891
http://dx.doi.org/10.2147/COPD.S63911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://www.ncbi.nlm.nih.gov/pubmed/24920891
http://dx.doi.org/10.2147/COPD.S63911

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