Helicobacter pylori CagL Y58/E59 Mutation Turns-Off Type IV Secretion-Dependent Delivery of CagA into Host Cells

The type IV secretion system (T4SS) is a major virulence determinant of the gastric pathogen Helicobacter pylori. The CagL protein is a specialized adhesin of the corresponding T4SS pilus, which establishes initial contact with the integrin β1 receptor on host target cells. Recent studies proposed t...

Descripción completa

Detalles Bibliográficos
Autores principales: Tegtmeyer, Nicole, Lind, Judith, Schmid, Benedikt, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Formal Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043526/
https://www.ncbi.nlm.nih.gov/pubmed/24893039
http://dx.doi.org/10.1371/journal.pone.0097782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043526/
https://www.ncbi.nlm.nih.gov/pubmed/24893039
http://dx.doi.org/10.1371/journal.pone.0097782

Ejemplares similares