Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse

Intervertebral discs (IVDs) are strong fibrocartilaginous joints that connect adjacent vertebrae of the spine. As discs age they become prone to failure, with neurological consequences that are often severe. Surgical repair of discs treats the result of the disease, which affects as many as one in s...

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Detalles Bibliográficos
Autores principales: Winkler, Tamara, Mahoney, Eric J., Sinner, Debora, Wylie, Christopher C., Dahia, Chitra Lekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043533/
https://www.ncbi.nlm.nih.gov/pubmed/24892825
http://dx.doi.org/10.1371/journal.pone.0098444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043533/
https://www.ncbi.nlm.nih.gov/pubmed/24892825
http://dx.doi.org/10.1371/journal.pone.0098444

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